A GUIDE FOR SOCIAL SCIENCE JOURNAL EDITORS ON EASING INTO OPEN SCIENCE


Schizophrenia syndrome due to C9ORF72 mutation case report: a cautionary tale and role of hybrid brain imaging!

Abstract Background Frontal variant frontotemporal dementia is a common cause of presenile dementia.A hexanucleotide expansion on chromosome 9 has recently been recognized as the most common genetic mutation cause of this illness.This sub-type tends to present psychiatrically with psychosis being a common presenting symptom before the onset of cogn

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Discovering covalent cyclic peptide inhibitors of peptidyl arginine deiminase 4 (PADI4) using mRNA-display with a genetically encoded electrophilic warhead

Abstract Covalent drugs can achieve high potency with long dosing intervals.However, concerns remain about side-effects associated with off-target reactivity.Combining macrocyclic peptides with covalent warheads provides a solution to minimise off-target reactivity: the peptide enables highly specific target binding, positioning Range Extender a we

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